ydbD [2019-06-21 10:04:34]

general stress protein, similar to manganese-containing catalase

Locus: BSU04430

Isoelectric point: 4.86

Molecular weight: 30.11 kDa

Protein length: 273 aa

Gene length: 822 bp

Function: survival of ethanol stress

Product: unknown

Essential: no

Synonyms

Genomic Context

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Categories containing this gene/protein

• Lifestyles → Coping with stress → General stress proteins (controlled by SigB)
• Lifestyles → Coping with stress → Resistance against oxidative and electrophile stress/ based on similarity

Gene

Coordinates: 495,740 496,561

The protein

Catalyzed reaction/ biological activity

• 2 H₂O₂ = O₂ + 2 H₂O (according to Swiss-Prot)

Protein family

• manganese catalase family (with CotJC and yjpc, according to UniProt)

Paralogous protein(s)

• YjqC, CotJC

Structure

• 1JKU (from Lactobacillus plantarum, 51% identity) PubMed

Expression and Regulation

Operons

• Genes: dctB-ydbD
  Description: PubMed

  Sigma factors

  • SigB: sigma factor, PubMed, in SigB regulon

  Regulation

  • induced by stress (SigB) PubMed

• Genes: ydbD

  Regulation

  • induced by stress (SigB) PubMed

Biological materials

Mutant

• BKE04430 (ydbD::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGTACCCATCTCCTTTTT, downstream forward: _UP4_TAAAGAGACAAGCCCAAAAC
• BKK04430 (ydbD::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGTACCCATCTCCTTTTT, downstream forward: _UP4_TAAAGAGACAAGCCCAAAAC

References

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